Glial Cells and Their Role in Health and Disease

The nervous system is composed of not only a diverse number of neurons but a potential greater diversity of “support cells” collectively called glia.  This years annual theme is intended  to encourage exploration of the emerging importance of these cells in health as well as disease.  The resources below are intended to be resources that may be used  by local chapters to foster discussion in their journal clubs and provide information that may be disseminated more broadly in public presentations or co-curricular activities. This is not an exhaustive list of resources.  Please let us know if you have additional resources that you can recommend (mkerchner@nurhopsi.com)


Recommended Resources

Glial Cells in Health and Disease
Nature Collection: 1 November 2017

Glia in mammalian development and disease.
Zuchero JB, Barres BA. Development. 2015 Nov 15;142(22):3805-9.
PMID: 26577203.

Reactive Astrocytes: Production, Function, and Therapeutic Potential.
Liddelow SA, Barres BA.
Immunity. 2017 Jun 20;46(6):957-967. doi: 10.1016/j.immuni.2017.06.006. Review.
PMID: 28636962

Microglia and macrophages in brain homeostasis and disease.
Li Q, Barres BA.
Nat Rev Immunol. 2018 Apr;18(4):225-242. doi: 10.1038/nri.2017.125.
PMID: 29151590

Glia as Architects of Central Nervous System Formation and Function
Allen, N.J. & Lysons, D.A.
Science, 2018 October 12; 362 (6411); 181-185. doi: doi: 10.1126/science.aat0473
[This article is accompanied by and extensive recommended reading list]

Wrapped to Adapt: Experience-Dependent Myelination.
Mount CW, Monje M.
Neuron. 2017 Aug 16;95(4):743-756. doi: 10.1016/j.neuron.2017.07.009.
PMID: 28817797

Mast Cells in the Developing Brain Determine Adult Sexual Behavior
Kathryn M. Lenz, Lindsay A. Pickett, Christopher L. Wright, Katherine T. Davis, Aarohi Joshi and Margaret M. McCarthy
Journal of Neuroscience 1 August 2018, 1176-18; DOI: https://doi.org/10.1523/JNEUROSCI.1176-18.2018

Alzheimer’s Disease and Sleep–Wake Disturbances: Amyloid, Astrocytes, and Animal Models
William M. Vanderheyden, Miranda M. Lim, Erik S. Musiek and Jason R. Gerstner
Journal of Neuroscience 21 March 2018, 38 (12) 2901-2910; DOI: https://doi.org/10.1523/JNEUROSCI.1135-17.2017


The 2018 Nu Rho Psi  Member Meeting Invited Speaker

Brad Zuchero, Ph.D.  [zucherolab.stanford.edu]

Zuchero-Headshot“Emerging roles of glia in health and disease”

Professor Zuchero is s an Assistant Professor in the Department of Neurosurgery, Stanford University School of Medicine. Brad has a longstanding interest in how cells in the brain interact to build a functional nervous system, regulate its function in adults, and how these interactions are perturbed in disease. Vist his laboratory website: here.


Awards

  • McKnight Scholar Award
  • Harry Weaver Neuroscience Scholar Award
  • Career Transition Award from the National MS Society
  • Life Sciences Research Foundation postdoctoral fellowship
  • Discovery Science Award and Pioneer Award from the Myelin Repair Foundation,
  • Research Award from the Marine Biological Laboratory in Woods Hole.

Join with us and Prof. Zuchero at the SFN 2018 Nu Rho Psi Member Meeting and Social 

11:30am – 1:00PM
Sunday, November 4, 2018
The Horton Grand Hotel –  https://www.hortongrand.com/
311 Island Avenue
San Diego, CA

directions to GHHotel